Decrease in PTSD symptom may lower Type 2 diabetes risk: Study.
Washington: Treatment for Post-Traumatic Stress Disorder (PTSD) can lower the risk of developing Type 2 diabetes, suggests a study, published in the journal 'JAMA Psychiatry.'
"Some long-term chronic health conditions associated with PTSD may be less likely to occur among patients who experience clinically meaningful symptom reduction either through treatment or spontaneous improvement," said Jeffrey Scherrer, a professor in Family and Community Medicine at SLU.
PTSD affects up to 12 per cent of civilians and nearly 30 per cent of the veteran population. Those with PTSD are at risk for other health issues and improvement in PTSD symptoms is associated with parallel improvements in depression, emotional well-being, sleep, blood pressure, and general physical health.
PTSD is associated with an increased risk of type 2 diabetes, which may be explained by the high prevalence of obesity, glucose dysregulation, inflammation, metabolic syndrome and depression among those diagnosed with PTSD versus those without PTSD.
This retrospective cohort study reviewed the Veterans Health Affairs medical record data from 2008 to 2015. The researchers randomly selected 5,916 cases from among a veteran patient population aged 18 to 70 who had more than two visits to PTSD specialty care between 2008 and 2012. The patients were followed through until 2015.
After applying eligibility criteria, 1,598 patients with PTSD and free of diabetes risk were available for analysis.
Clinically meaningful symptom reduction is a decrease of 20 points on the PTSD Checklist score. The research found the results were independent of numerous demographic, psychiatric, and physical comorbidities.
The sample was 84.3 percent male, 66 percent Caucasian and 22 percent African-American. The mean age of the patients was 42.
"In patients with only PTSD, clinically meaningful PCL decrease is associated with a lower risk for diabetes and in patients with PTSD and depression, we found improvement in PTSD was coupled with a decrease in depression," Scherrer said.
"Thus the decreased risk of type 2 diabetes appears to follow large PTSD symptoms decrease and in patients with both PTSD and depression, improvement in both conditions may be necessary to reduce the risk for type 2 diabetes."