Tuesday, Aug 04, 2020 | Last Update : 05:42 PM IST

133rd Day Of Lockdown

Maharashtra45019628703015842 Tamil Nadu2632222022834241 Andhra Pradesh166586886781537 Karnataka139571625002594 Delhi1384821242544021 Uttar Pradesh97362553931778 West Bengal78232548181731 Telangana6766048609551 Gujarat64684476632504 Bihar5956738508336 Rajasthan4555532051719 Assam4527633429109 Haryana3717330470440 Odisha3629723074248 Madhya Pradesh3428524099900 Kerala268731527885 Jammu and Kashmir2200614032407 Punjab1852711882442 Jharkhand135004794125 Chhatisgarh9820725661 Uttarakhand7800453890 Goa6816487656 Tripura5389360527 Puducherry3982241156 Manipur292017667 Himachal Pradesh2818165813 Nagaland21296574 Arunachal Pradesh175810633 Chandigarh116070619 Meghalaya9022645 Sikkim6882971 Mizoram4962660
  Newsmakers   22 Dec 2018  Cure for Aids: Scientists successfully destroy HIV-infected cells in major breakthrough

Cure for Aids: Scientists successfully destroy HIV-infected cells in major breakthrough

THE ASIAN AGE
Published : Dec 22, 2018, 4:36 pm IST
Updated : Dec 22, 2018, 4:36 pm IST

According to researchers they have successfully destroyed cells infected with virus, typically treated with antiretroviral drugs.

The study was funded by the Institut Pasteur, AmfAR (American Foundation for AIDS research) and Sidaction.
 The study was funded by the Institut Pasteur, AmfAR (American Foundation for AIDS research) and Sidaction.

In a stunning revelation, scientists have announced a potentially major breakthrough in the fight against HIV.

According to eesearchers at Paris' Institut Pasteur, they have successfully destroyed cells infected with the virus, which is typically treated with antiretroviral drugs.

 

The drugs are unable to remove the virus from the body, but medical journal Cell Metabolism published findings which announced that scientists had found a way to eliminate infected 'reservoir' cells. 

In a release uploaded to EurekaAlert, an Institut Pasteur spokesperson said that the antiretroviral treatment used today is designed to block HIV infection but it is not able to eliminate the virus from the body.

He added, “The virus remains in reservoirs - the CD4 T lymphocyte immune cells, the main targets of HIV.”

Notably, HIV targets cells with high metabolic activity and 'hijacks' their energy in order to multiply.

 

The release goes on to state, “Thanks to metabolic activity inhibitors, the researchers have managed to destroy these infected cells, or "reservoirs", ex vivo.”

It concludes by stating that the research opens the possibility of new pathways towards remission by eliminating the 'reservoir' cells.

The next step in research will be assessing the potential of metabolic inhibitors 'in vivo' - tested on living organisms.

Theoretically, if the viral load is low enough, destroying the cell HIV hides in and draws energy from could keep it from spreading in the body and, perhaps, eradicate it altogether, it is hoped.  

 

The study was funded by the Institut Pasteur, AmfAR (American Foundation for AIDS research) and Sidaction.

Tags: aids, hiv, hiv infected cells, paris' institut pasteur, hiv cure, hiv nreakthrough, amfar, sidaction, reservoir cells, health and well being